Our activities and studies

AI4HealthyCities Basel

PD Dr. med. Julia Bielicki

 -

Data Science-Implementation hybrid

SwissPedHealth

Pediatric Personalized Research Network Switzerland (SwissPedHealth) – a Joint Pediatric National Data Stream Work Package 1 – Infrastructure and Governance

PD Dr. med. Julia Bielicki

 -

national, multicenter

SwissPedHealth PREPP

SwissPedHealth Personalized Pediatric Primay care PREPP

Prof. Dr. med. Jan Bonhoeffer

-

national, multicenter

SPEARHEAD

SwissPandEmic&AmR Health Economy Awareness Detect
Subproject 2: UTI Risk Prediction Model

PD Dr. med. Julia Bielicki

-

national, multicenter

VERDI

SARS-CoV2 variants Evaluation in pRegnancy and paeDIatrics cohorts – An evaluation of school-based mass PCR testing in Baselland

PD Dr. med. Julia Bielicki

-

population-based evaluation

AcneDect

Acne detection software

Prof. Dr. med. Alexander Navarini

40 (20 in Basel)

National, multicenter

KIDS-STEP

A randomised placebo-controlled multi-centre effectiveness trial of adjunct betamethasone therapy in hospitalised children with community acquired pneumonia (CAP)

PD Dr. med. Julia Bielicki

700 (112 in Basel)

International, multicenter

ADEQUATE

Advanced Diagnostics for Enhanced Quality of Antibiotic Prescription in Respiratory Tract Infections in Emergency rooms

PD Dr. med. Julia Bielicki

500

International, multicenter

ALARUM

Active one health surveillance in LMICs to monitor and predict Antimicrobial Resistance Using Metagenomics

CH: PD Dr. med. Julia Bielicki

>1000

International, multicenter

MYTHIC

A randomized controlled non-inferiority trial of placebo versus macrolide antibiotics for Mycoplasma pneumoniae infection in children with community-acquired pneumonia

PD Dr. med. Julia Bielicki

380

National, multicenter

BENCHMARK II – UTI

Routine antibiotic prescription and resistance monitoring in primary care physicians: A nationwide pragmatic randomized controlled trial

PD Dr. med. Julia Bielicki

-

population-based

FIONA

A 6-month multicenter, randomized, double-blind, placebo-controlled study to evaluate the efficacy, safety and PK/PD of an age-and body weight-adjusted oral finerenone regimen, in
addition to an ACEI or ARB, for the treatment of children, 6 months to <18 years of age, with chronic kidney disease and proteinuria

Dr. med. Alexandra Goischke

2

International, multicenter

FIONA OLE

An 18-month, open-label, single-arm safety extension study of an age-and bodyweightadjusted oral finerenone regimen, in addition to an ACEI or ARB, for the treatment of children and young adults from 1 to 18 years of age with chronic kidney disease and proteinuria

Dr. med. Alexandra Goischke

2

International, multicenter

 Midazolam

Observational study to understand acceptability of various available midazolam formulations (syrup, rectal suppository, oro-dispersible minitablet) in clinical practice

Dr. med. Svetlana Beglinger

 70

National, multicenter

PICSS

Post Intensiv Care Syndrome in Swiss Pediatric survivors and their Families

Prof. Dr. med. Daniel Trachsel

60

international, multicenter

RoProp

Oral propanolol for the prevention of high-grade retinopathy of prematurity

Prof. Dr. med. Sven Schulzke

National, multicenter

NeoDeco

Optimising kangaroo care to reduce neonatal severe infection/sepsis and resistant bacterial colonisation among high-risk infants in neonatal intensive care: a pragmatic, multicentre, parallel cluster randomised hybrid implementation–effectiveness trial

Dr. med. Kerstin Jost

 >5000

International, multicenter

PASTA

Paediatric Arteriopathy Steroid Aspirin High dose steroids in children with stroke and unilateral focal arteriopathy

Prof. Dr. med.  Alexandre Datta

24 (4 in Basel)

International, multicenter

POOMAS

Prognosis, treatment, and mechanisms in an international paediatric onset opsoclonus myoclonus ataxia syndrome (POOMAS) database and virtual biobank

Prof. Dr. Andrea Klein

open register

International, multicenter

SPHYNCS

Swiss Primary Hypersomnolence and Narcolepsy Study

Prof. Dr. med. Alexandre Datta

(2-5 in Basel)

national, multicenter

SCCSS

Swiss Childhood cancer Survivor Study-Follow up, Follow Up- Lungengesundheit nach Krebs im Kindesalter

Prof. Dr. med. Nicolas von der Weid

 60-80

National, Multicenter

SwissPearl

Studie zur Untersuchung der Lungenentwicklung bei Kindern u. Jugendlichen während und nach Krebstherapie

Dr. med. Christina Schindera

150

National, multicenter

RHCG

Multicenter, open-label, efficacy, tolerability and pharmacokinetic study of subcutaneous Ixekizumab with Adalimumab reference arm in children with juvenile idiopathic arthritis subtypes of enthesitis- related arthritis (including juvenile-onset ankylosing spondylitis) and juvenile psoriatic arthritis.

Dr. med. Andreas Wörner

100 (5 in Basel)

International, multicenter

 SwissPedRecovery

 SWISSPED-RECOVERY: Randomised Evaluation of COVID-19 Therapy (RECOVERY) in Children With PIMS-TS in Switzerland

 PD Dr. med. Julia Bielicki

 76

 national, multicenter